Recombinant BMI1 Monoklonale Antilichaam

This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1) . This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene.

BMI1

P35226

Human

A synthetic peptide corresponding to the center region of the Human BMI1

RNF; BMI; PCGF; flvi-2/bmi; FLVI2/BMI; BMI1; FLVI2/BMI1; PCGF4; RNF51; flvi-2/bmi-1

4B3

Unconjugated

IHC-P

Cell Biology; Epigenetics and Nuclear Signaling; Stem Cells; Cancer

Protein A

1 mg/mL

IHC-P 1:100-1:500

0.2 μm filtered solution in PBS

Ice bag

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

https://789.bio/eb/U0tSpUOF

IgG