Recombinant c-Myc Monoklonale Antilichaam

MYC (v-myc avian myelocytomatosis viral oncogene homolog) Homo sapiens The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.

C-Myc

P01106

Human; Mouse; Rat

Recombinant Human c-Myc protein

BHLHe; MYC BHLHE; MRTL; MYCC; bHLHe39; c-Myc; MYC; MYC BHLHE39; AU016757; Avian myelocytomatosis viral oncogene homolog; c Myc; Class E basic helix-loop-helix protein 39; Myc protein; Myc proto oncogene protein; Myc proto-oncogene protein; Myc2; myc-related translation/localization regulatory factor; Myelocytomatosis oncogene; Niard; Nird; Oncogene Myc; OTTHUMP00000158589; Proto-oncogene c-Myc; Protooncogene homologous to myelocytomatosis virus; RNCMYC; Transcription factor p64; Transcriptional regulator Myc-A; V-Myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog (avian) ; V-myc myelocytomatosis viral oncogene homolog (avian)

8D4

Unconjugated

WB; IHC

Epigenetics and Nuclear Signaling; Stem Cells; Cancer

Protein A

0.2 mg/mL

IHC 1:200-1000; WB 1:1000-5000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/xLXHY5v9

48 kDa

60 kDa

IgG, κ