Recombinant CALML5 Monoklonale Antilichaam

Calmodulin-like protein 5, also known as Calmodulin-like skin protein, CALML5 and CLSP, is a protein which contains fourEF-hand domains. CALML5/CLSP is particularly abundant in the epidermis where its expression is directly related to keratinocyte differentiation.The expression is very low in lung. CALML5/CLSP binds calcium. It may be involved in terminal differentiation of keratinocytes. Coxsackievirus and adenovirus receptor (CAR) is a member of the immunoglobulin (Ig) superfamily and a component of epithelial tight junction. CAR functions as a primary receptor for coxsackievirus B and adenovirus (Ad) infection. CALML5/CLSP is closely related to CAR. The structure and dynamics of human calmodulin-like skin protein CALML5/CLSP have been characterized by NMR spectroscopy. The mobility of CALML5/CLSP has been found to be different for the N-terminal and C-terminal domains. The N-terminal domain is characterized by four stable helices, which experience large fluctuations. This is shown to be due to mutations in the hydrophobic core. The overall N-terminal domain behavior is similar both in the full-length protein and in the isolated domain.

CALML5

Q9NZT1

Human

Recombinant Human CALML5 protein

Calmodulin like; Calmodulin-like protein; CALML; CALL5_HUMAN; Calmodulin like 5; Calmodulin-like protein 5; Calmodulin-like skin protein; CLSP; CALML5

5F5

Unconjugated

FCM; ICC/IF

Signal Transduction; Cell Biology

Protein A

1 mg/mL

ICC/IF 1:20-1:100; FCM 1:25-1:100

0.2 μm filtered solution in PBS

Ice bag

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

https://789.bio/eb/PAcdGWvg

IgG