Recombinant canine IL-31 eiwit

IL31, also known as interleukin 31, is a member of the gp130/interleukin-6 cytokine family that is produced by cell types such as T helper 2 lymphocytes and cutaneous lymphocyte antigen positive skin homing T cells. IL-31 signals via a heterodimeric receptor complex composed of a gp130 related molecule termed IL-31RA (also GPL and GLMR) and an Oncostatin M receptor (OSM R beta) . The IL-31 receptor is constitutively expressed by keratinocytes and upregulated by IFN gamma on monocytes. Recombinant canine IL31, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Interleukin-31, IL-31

Baculovirus

Canine

His-Tag

SDS-PAGE

1 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

16.1 kDa (142aa)

IL 31, IL31, IL-31, Interleukin-31, Interleukin 31, Interleukin31, ATGP3570-10 µg, ATGP3570-20 µg, ATGP3570-50 µg, ATGP3570-100 µg, ATGP3570-250 µg, ATGP3570-500 µg, ATGP3570-1 mg, ATGP3570-010, ATGP3570-020, ATGP3570-050, ATGP3570-100, ATGP3570-250, ATGP3570-500, ATGP3570-01M

MizunoT., et al, (2009) Vet. Immunol. Immunopathol. 131:140-143.; ; Gonzales AJ., et al, (2013) Vet. Dermatol. 24:48-53.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Hormones & Cytokines

NP_001159386

C7G0W1

Canine

Ser24