Recombinant canine IL-31 eiwit

IL31, also known as interleukin-31, is a cytokine with an anti-parallel four-helix bundle structure in the gp130/IL-6 cytokine family. It shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. This protein is mainly associated with activated T cells and is preferentially expressed by type 2 helper T cells (Th2) . This protein is an inflammatory cytokine that helps trigger cell-mediated immunity against pathogens. It has also been identified as a major player in a number of chronic inflammatory diseases, including atopic dermatitis. Recombinant Canine IL31 was expressed in insect cell and purified by using conventional chromatography techniques.

Interleukin-31, IL-31

Baculovirus

Canine

Non-Tagged

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

15.3 kDa (136aa)

IL 31, IL31, IL-31, Interleukin-31, Interleukin 31, Interleukin31, ATGP3888-10 µg, ATGP3888-20 µg, ATGP3888-50 µg, ATGP3888-100 µg, ATGP3888-250 µg, ATGP3888-500 µg, ATGP3888-1 mg, ATGP3888-010, ATGP3888-020, ATGP3888-050, ATGP3888-100, ATGP3888-250, ATGP3888-500, ATGP3888-01M

Dillon SR., et al, (2004) Nat. Immunol. 5:752-760.; ; Diveu C., et al, (2004) Eur. Cytokine Netw. 15:291-302.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol

Hormones & Cytokines

NP_001159386.1

C7G0W1

Canine

Ser24

SHMAPTHQLP PSDVRKIILE LQPLSRGLLE DYQKKETGVP ESNRTLLLCL TSDSQPPRLN SSAILPYFRA IRPLSDKNII DKIIEQLDKL KFQHEPETEI SVPADTFECK SFILTILQQF SACLESVFKS LNSGPQ