Recombinant Caspase-7 monoklonaal antilichaam

Caspase-7, also named as CMH-1, Mch3 and ICE-LAP3, has been identified as a major contributor to the execution of apoptosis. Caspase-7, like caspase-3, is an effector caspase that is responsible for cleaving downstream substrates such as ADP-ribose polymerase and PARP. During apoptosis, caspase-7 is activated through proteolytic processing by upstream caspases at Asp23, Asp198, and Asp206 to produce the mature subunits. Similar to caspase-2 and -3, caspase-7 preferentially cleaves substrates following the recognition sequence DEVD.

Caspase-7

P97864

Rat; Mouse

Recombinant human Caspase-7 fragment

Mch; Lice; CASP; Lice2; Mch3; Casp7; CASP-7; Caspase 7; CMH-1; ICE-LAP3

A586

Unconjugated

WB; IHC

Protein A purified

1 mg/mL

WB 1:500-1:1000; IHC 1:200-1:1000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/LwbX5HNj

34 kDa

34 kDa

IgG, κ