Recombinant Caspase-9 monoklonaal antilichaam

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.

Caspase-9

P55211

Human; Mouse

Recombinant Human Caspase-9 protein

MCH; Apoptotic protease Mch; PPP1R; ICE-LAP; CASP9; APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56; caspase-9; Caspase 9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3 (APAF-3) ; ICE-like apoptotic protease 6 (ICE-LAP6) ; Apoptosis related cysteine peptidase; Apoptotic protease-activating factor 3; Caspase 9 apoptosis related cysteine peptidase; Caspase 9 Dominant Negative; Caspase 9c; Caspase-9 subunit p10; ICE LAP6; ICE like apoptotic protease 6; ICE-like apoptotic protease 6; protein phosphatase 1; regulatory subunit 56; RNCASP9

6C11

Unconjugated

WB; IHC

Cell Biology; Cancer; Metabolism

Protein A

0.2 mg/mL

WB 1:1000-1:5000; IHC 1:500-1:1000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/iyXrx0u9

46 kDa

40 kDa

IgG, κ