Recombinant Cathepsine B Monoklonale Antilichaam

Cathepsin B is a member of the C1 family of peptidases. This protein is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP) . Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer's disease. Overexpression of Cathepsin B has been associated with esophageal adenocarcinoma and other tumors. Both Cathepsin B and Cathepsin L are involved in the cleavage of the spike protein from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) upon its entry to the human host cell.

Cathepsin B

P07858

Human

Recombinant human Cathepsin B fragment

APPS; CPSB; Cathepsin B; CTSB; APP Secretase; CathepsinB; CATB; Cathepsin B1; cysteine protease; Amyloid precursor protein secretase; Cathepsin B heavy chain; OTTHUMP00000116009; OTTHUMP00000229510; OTTHUMP00000229511; OTTHUMP00000229512; OTTHUMP00000229514; OTTHUMP00000229515; OTTHUMP00000229516; Preprocathepsin B

A464

Unconjugated

WB

Neuroscience; Signal Transduction; Cancer; Kits; Lysates; Other

Protein A purified

1 mg/mL

WB 1:1000-1:5000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/BeZphLZZ

38 kDa

38 kDa

IgG, κ