Recombinant CBX4 monoklonaal antilichaam
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
CBX4 is a component of the PRC1 complex, which together with Ring1 strongly enhances the E3 ubiquitin ligase activity of the Ring2 catalytic subunit. CBX4 itself is a SUMO E3 ligase, and its function influences EMT, DNA damage response, tumor angiogenesis, and self-renewal. E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. It is involved in the SUMOylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression.
CBX4
O00257
• Rabbit
Human; Rat; Mouse
Recombinant human CBX4 fragment
Cbx; CBX4
• Monoclonal
• Recombinant
A527
Unconjugated
WB; IHC
Epigenetics and Nuclear Signaling
Protein A purified
1 mg/mL
WB (human) 1:500-1:1000; WB (rat) 1:1000-1:5000; IHC 1:200-1:1000
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Ice bag
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
https://789.bio/eb/46Dz9LrJ
61 kDa
61 kDa
IgG, κ
Beschrijving
Recombinant CBX4 monoklonaal antilichaam Beschikbaar in 50 µL. Bestel eenvoudig online met snelle levering.
Specificaties
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ExactaCruz® Pipette Tip Reload System, 50-1250 μl, case
sc-201714
80 Racks/Case
Disc Membrane Hydrophobic PTFE, 0.22μm
CPTB14222
50 PCS
Rat Serum Albumin
CSB-NP000101r-01
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Denhardt's Solution (50X)
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FKBP4, ID (FK506-binding Protein 4, Peptidyl-prolyl cis-trans Isomerase FKBP4, PPIase FKBP4, Rotamase, HSP-binding Immunophilin, HBI, FKBP52 Protein, 52kD FK506-binding Protein, 52kD FKBP, FKBP-52, 59kD Immunophilin, FKBP59, p59 Protein, FKBP-4, FKBP52)
MBS623609-01
0.2 mL
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sc-141806
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sc-141806-PR
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D030016E14Rik (m) -PR
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10 µM - 20 µL
Compound N003-0017
T131382-01
1 mg
Compound N003-0017
MBS5796320
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