Recombinant CD46 Monoklonale Antilichaam

The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.

CD46

P15529

Human

Recombinant Human CD46 protein

MIC; AHUS; TRA2.; AHUS2; MCP; MIC10; TLX; TRA2.10; CD46; CD46 molecule; Membrane Cofactor Protein; Trophoblast Leukocyte Common Antigen

10A2

Unconjugated

IHC-P; ICC/IF

Immunology

Protein A

1 mg/mL

IHC-P 1:100-1:500; ICC/IF 1:20-1:100

0.2 μm filtered solution in PBS

Ice bag

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

https://789.bio/eb/EtJ1qkNC

IgG