Recombinant CHOP monoklonaal antilichaam

This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.

CHOP

P35638

Human; Mouse; Rat

Recombinant Human CHOP protein

DDIT; GADD; DNA damage inducible transcript; DDIT3; CEBPZ; CHOP; CHOP-10; CHOP10; GADD153; C/EBPzeta; DDIT3 / CHOP; DNA damage inducible transcript 3; CEBPZ; CHOP; CHOP10; CHOP-10; DNA damage inducible transcript 3; GADD153; C/EBP homologous protein; C/EBP Homology Protein; C/EBP zeta; C/EBP-homologous protein; C/EBP-homologous protein 10; CCAAT/enhancer binding protein homologous protein; CHOP 10; DDIT 3; DDIT-3; DNA damage-inducible transcript 3 protein; GADD 153; Growth Arrest and DNA Damage Inducible Protein 153; Growth arrest and DNA damage inducible protein GADD153; Growth arrest and DNA damage-inducible protein GADD153; MGC4154

7A2

Unconjugated

WB; IHC

Epigenetics and Nuclear Signaling; Stem Cells; Developmental Biology; Metabolism

Protein A

0.2 mg/mL

IHC 1:1000-1:4000; WB 1:1000-1:5000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/btpzspVS

19 kDa

30 kDa

IgG, κ