Recombinant Claved Caspase-3 (Asp175) Monoklonale Antilichaam

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

Cleaved Caspase-3

P42574

Human; Mouse; Rat

Recombinant Human Cleaved Caspase-3 (Asp175) protein

SCA; CPP; Caspase-3 p; SREBP cleavage activity; Caspase; Caspase-; CPP32; CPP32B; SCA-1; Active Caspase 3; CASP3; active Caspase-3; Caspase 3; Caspase-3 p12; caspase-3; Apoptain; Yama; CASP-3; Apopain; Protein Yama; SREBP cleavage activity 1; Caspase-3 subunit p17; Caspase-3 subunit p12; caspase-3; CPP32; CPP32B; SCA-1; A830040C14Rik; apoptosis-related cysteine peptidase; apoptosis-related cysteine protease; apoptosis-related cysteine protease a; Casp3a; CC3; CPP-32; Cysteine protease CPP32; EC 3.4.22.56; LICE; mldy; OTTHUMP00000165052; OTTHUMP00000165053; OTTHUMP00000165054; PARP cleavage protease; Procaspase3; SCA 1; Caspase-3

4F4

Unconjugated

WB; IHC

Neuroscience; Cell Biology; Cancer; Metabolism

Protein A

0.2 mg/mL

IHC 1:200-1:1000; WB 1:1000-1:5000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/5z03XQh7

17 kDa,19 kDa

17 kDa,19 kDa

IgG, κ