Recombinant Clusterine beta Chain Monoklonale Antilichaam

Clusterin (CLU) also named as apolipoprotein J, is a multifunctional glycoprotein that is expressed ubiquitously in most tissues. Clusterin functions as a secreted chaperone protein that interacts with and stabilizes stress-induced proteins to prevent their precipitation. Research studies show that clusterin plays a protective role in Alzheimer’s disease by sequestering amyloid β (1-40) peptides to form long-lived, stable complexes, which prevents amyloid fibril formation.In addition to the secreted protein, several intracellular isoforms are localized to the nucleus, mitochondria, cytoplasm and ER. The subcellular distribution of these multiple isoforms leads to the diversity of clusterin functions. Additional studies report that clusterin is involved in membrane recycling, cell adhesion, cell proliferation, apoptosis, and tumor survival.

Clusterin beta Chain

P10909

Rat; Mouse

Recombinant human Clusterin beta Chain fragment

KUB; AAG; Ku70-binding protein; Sulfated glycoprotein; Complement-associated protein SP; Testosterone-repressed prostate message; NA1/NA; SGP; CLU; AAG4; APO-J; APOJ; CLI; CLU1; CLU2; KUB1; NA1/NA2; SGP-2; SGP2; SP-40; TRPM-2; TRPM2; clusterin; CLUS; Aging-associated gene 4 protein; Apolipoprotein J; Complement cytolysis inhibitor; Complement-associated protein SP-40; Ku70-binding protein 1; Sulfated glycoprotein2; Testosterone-repressed prostate message 2; Complement cytolysis inhibitor a chain; Clusterin alpha chain; Complement cytolysis inhibitor b chain; APOJ CLI; Sulfated glycoprotein 2

A616

Unconjugated

WB

Immunology; Cardiovascular; Signal Transduction; Cancer; Metabolism

Protein A purified

1 mg/mL

WB 1:500-1:1000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/hud6mGEA

52 kDa

35 kDa

IgG, κ