Recombinant Collageen IV Monoklonale Antilichaam

This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants.

Collagen IV

P02462

Human

Recombinant Human Collagen IV protein

COL4A; POREN; alpha 1 chain; Arresten; COL4A1 NC1 domain; Collagen alpha-1 (IV) chain; Collagen IV alpha-1 polypeptide; Collagen of basement membrane; HANAC; ICH; POREN1; COL4A1; Type-IV Collagen

10F10

Unconjugated

WB; IHC

Signal Transduction; Stem Cells; Cancer

Protein A

0.2 mg/mL

IHC 1:200-1000; WB 1:1000-5000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/6BKXehF6

160 kDa

200 kDa

IgG, κ