Recombinant CUL4A/B Monoklonale Antilichaam

CUL4A is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins (Liu et al., 2009 [PubMed 19481525]) .[supplied by OMIM, Oct 2009], CUL4B is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene.

CUL4A/B

Q13619; Q13620

Human; Mouse; Rat

Recombinant Human CUL4A/B protein

CUL4A; cullin-4A;2810470J21Rik; AW495282; CUL 4A; CUL-4A; Cul4a protein; MGC36573; MGC64071; CUL4A/B

9D6

Unconjugated

WB; IHC

Cell Biology

Protein A

0.2 mg/mL

IHC 1:200-1:1000; WB 1:2000-1:10000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/jDp7PWz2

88104 kDa

88 kDa,104 kDa

IgG, κ