Recombinant Cycline D2 Monoklonale Antilichaam

Cyclin D2 (CCND2) belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. CCND2 forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. CCND2 has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. High level expression of CCND2 was observed in ovarian and testicular tumors.

Cyclin D2

P30279

Human; Rat

Recombinant human Cyclin D2 fragment

CCND; KIAK; MPPH; G1/S-specific cyclin-D; cyclin D; CCND2; KIAK0002; MPPH3; cyclin D2; G1/S-specific cyclin-D2

A542

Unconjugated

WB; IHC

Cell Biology; Epigenetics and Nuclear Signaling; Cancer

Protein A purified

1 mg/mL

WB 1:2000-1:10000; IHC 1:100-1:1000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/6FVWng2z

33 kDa

36 kDa

IgG, κ