Recombinant Drosha Monoklonale Antilichaam

DROSHA (drosha ribonuclease III) Homo sapiens This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer.

Drosha

Q9NRR4

Human; Mouse; Rat

Recombinant Human Drosha protein

ETOHI; DROSHA; ETOHI2; HSA242976; RANSE3L; RN3; RNASE3L; RNASEN; Drosha double stranded RNA specific endoribonuclease; Drosha ribonuclease type III; Nuclear RNase III Drosha; p241; Protein Drosha; Putative protein p241 which interacts with transcription factor Sp1; Putative ribonuclease III; Ribonuclease 3; Ribonuclease III; Ribonuclease III nuclear; Ribonuclease type III nuclear; RibonucleaseIII; RN 3; RNase 3; RNase III; RNase3; RnaseIII; RNaseIII; RNC; Drosha

11G11

Unconjugated

WB; IHC

Epigenetics and Nuclear Signaling

Protein A

0.2 mg/mL

IHC 1:200-1:1000; WB 1:2000-1:10000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/m9mdaqDY

159 kDa

159 kDa

IgG, κ