Recombinant E.coli Tryptofaan Synthase Proteïne (His Tag)

Tryptophan synthase is a multienzyme α2β2 complex composed of two protein subunit. Tryptophan synthase catalyzes the last two steps in the synthesis of L-tryptophan (L-Trp) . The α-subunit catalyzes cleavage of 3-indole-d-glycerol 3′-phosphate (IGP) to give indole and D-glyceraldehyde 3′-phosphate (G3P) . Indole is then transferred through a 25-hydrophobic tunnel to the β-subunit. The β2 subunit contains pyridoxal 5'-phosphate and catalyzes several pyridoxal 5'-phosphate-dependent reactions, including/3-elimination reactions 6 and a thiol-dependent transamination reaction. This enzyme is commonly found in Eubacteria, Archaebacteria, Protista, Fungi, and Plantae, but is absent from Animalia. As humans do not have tryptophan synthase, this enzyme has been explored as a potential drug target.

Tryptophan Synthase

Tryptophan synthase; Tryptophan synthetase

P0A877; P0A879

P0A877&P0A879

E.coli

N-His

Met1-Ser268&Thr2-Ile397

< 1.0 EU per μg of the protein as determined by the LAL method.

> 95 % as determined by reducing SDS-PAGE.

Not validated for activity

Not Applicable

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

https://789.bio/eb/4u5WfL

28.7&43.8 kDa

28&40-50 kDa

Supplied as a 0.2 μm filtered solution of PBS, pH7.4.

E.coli