Recombinant enkelketenige harttroponine I-C 2e generatie

Source : Escherichia Coli. Recombinant Single Chain Cardiac Troponin I-C 2nd generation produced in E.Coli is a single, non-glycosylated, polypeptide chain (aa28-110-Linker-cTnC), having a molecular weight of 30kDa.1mg of scIC2 is equivalent to 0.82mg of full length human cardiac TNI on a molar basis.The scIC2 is purified by proprietary chromatographic techniques. Troponin Complex is a heteromeric protein playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, Troponin I, Troponin T and TroponinC. Each subunit is responsible for part of Troponin Complex function. E.g. Troponin I inhibits ATP-ase activity of acto-myosin.Troponin T and Troponin Iare presented in cardiac muscles in different forms than in skeletal muscles. Purified subunits of rcTnI, rcTnC and rcTnT are recomplexed in vitro under appropriate conditions.

Troponin I cardiac muscle||Cardiac troponin I||TNNI3||TNNC1||CMH7||RCM1||cTnI||CMD2A||MGC116817||Troponin C slow skeletal and cardiac muscles||TN-C||TNNC1||TNNC||TNC||CMD1Z.

Greater than 91.0% as determined by SDS-PAGE.

The protein solution contains 20mM Tris-HCl, 250mM NaCl and 50% glycerol, pH 7.5.

ScIC2 although stable at 10°C for 7 days, should be stored below -18°C. Please prevent freeze-thaw cycles.