Recombinant FDPS/Farnesyldifosfaat Synthase Monoklonale Antilichaam

This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 18 and X. Multiple transcript variants encoding different isoforms have been found for this gene.

FDPS

P14324

Human

Recombinant Human FDPS / Farnesyl Diphosphate Synthase protein

KIAA; POROK; FDPS; FPPS; FPS; POROK9; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyl diphosphate synthetase; Farnesyl pyrophosphate synthase; Farnesyl pyrophosphate synthetase; FPP synthase; FPP synthetase; FPPS_HUMAN; Geranyltranstransferase; KIAA1293

11D13

Unconjugated

WB; FCM; ICC/IF; IP

Cardiovascular; Signal Transduction; Cancer; Metabolism

Protein A

1 mg/mL

WB 1:500-1:2000; FCM 1:25-1:100; ICC/IF 1:20-1:100; IP 1-4 μL/mg of lysate

0.2 μm filtered solution in PBS

Ice bag

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

https://789.bio/eb/ib0n8ZXG

48 kDa

38 kDa

IgG