Recombinant fosfor-CD31 (Tyr713) Monoklonale antilichamen

CD31, also named as Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1), a member of the Ig superfamily of cell adhesion molecules, is expressed by circulating platelets, monocytes, neutrophils, some T cells, and endothelial cells and modulates cell adhesion, endothelial cell migration, and angiogenesis. CD31 is phosphorylated on Tyr686 at the cytoplasmic carboxy-terminal tail upon various stimuli (e.g. mechanical or oxidative stress), presumably by Src family members. The tyrosine phosphorylation mediates associations with a number of SH2 domain-containing binding partners such as PI3 kinase, SHIP, PLCγ, and SHP-2. Thus, CD31 serves as a scaffold for various signaling molecules.

Phospho-CD31 (Tyr713)

P16284

Human

Phosphorylated human CD31 (Tyr713) peptide

PECA; cluster of differentiation; PECAM1; CD31; CD31/EndoCAM; GPIIA; PECA1; PECAM-1; endoCAM; cluster of differentiation 31; Platelet endothelial cell adhesion molecule; endocam; Adhesion molecule; CD31 antigen; CD31 EndoCAM; FLJ34100; FLJ58394; GPIIA'; PECAM; Pecam 1; PECAM 1 CD31 EndoCAM; PECAM1; Platelet and endothelial cell adhesion molecule 1; Platelet/endothelial cell adhesion molecule 1; CD31; EndoCAM; GPIIA; PECA1; PECAM-1; Platelet endothelial cell adhesion molecule

A817

Unconjugated

WB

Cardiovascular; Signal Transduction; Stem Cells; Cancer

Protein A purified

1 mg/mL

WB 1:1000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/UanXF55v

83 kDa

130 kDa

IgG, κ