Recombinant fosfor-eIF2α (Ser51) Monoclonaal antilichaam

The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161) . The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]) .[supplied by OMIM, Feb 2007]

EIF2S1

P05198

Human

A synthetic phosphopeptide corresponding to residues around Ser51 of human Phospho-eIF2α.

EIF2S; EIF; EIF-2; EIF-2A; EIF-2alpha; EIF2; EIF2A; EIF2S1; EIF 2; EIF 2 alpha; EIF 2A; EIF 2alpha; EIF2 alpha; eIF-2-alpha; Eukaryotic translation initiation factor 2 subunit 1; Eukaryotic translation initiation factor 2 subunit 1 alpha; Eukaryotic translation initiation factor 2 subunit 1 alpha 35kDa; Eukaryotic translation initiation factor 2 subunit alpha; IF2A

4B11

Unconjugated

WB

Epigenetics and Nuclear Signaling

Protein A

1 mg/mL

WB 1:1000-1:10000

10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5

Ice bag

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

https://789.bio/eb/jxzIBMOh

36 kDa

36 kDa

IgG