Recombinant fosfor-histone H2A.X (Ser139) Monoklonale antilichamen

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

H2AX

P16104

Human

A synthetic peptide corresponding to residues around Ser139 of Human Phospho-Histone H2A.X

H2A.X; H2A/X; H2AX; Histone H2AX; H2AFX; gamma H2A.X; γH2AX

12G4

Unconjugated

WB; IHC-P

Epigenetics and Nuclear Signaling

Protein A

1 mg/mL

WB 1:2000-1:20000; IHC-P 1:1000-1:5000

10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5

Ice bag

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

https://789.bio/eb/qRnt0zRY

15 kDa

15 kDa

IgG