Recombinant fosfor-NF-κB p65 (Ser536) Monoklonale antilichamen

65 is a subunit of the nuclear factor kappa B. The transcription factor NFkB is widely recognized as a critical mediator of immune and inflammatory responses. In most cell types, NFkB is found in the cytoplasm where it is associated with an inhibitory protein known as IkB. An impressive variety of stimuli (tumor necrosis factor, interleukin 1, T cell activation signals, bacterial endotoxins, viral transforming proteins, certain growth factors and reactive oxygen intermediates) lead to the rapid nuclear accumulation of NFkB by the induced phosphorylation and subsequent degradation of IkB.

RELA

Q04206

Human

A synthetic phosphopeptide corresponding to residues around Ser536 of the Human NF-κB p65

NFKB; Transcription factor p; Nuclear factor of kappa light polypeptide gene enhancer in B-cells; NF-kB p; NFKB3; p65; NF-kB p65; RELA; CMCU; Transcription factor p65; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; NFKB3; p65; transcription factor p65; Avian reticuloendotheliosis viral (v rel) oncogene homolog A; MGC131774; NF kappa B p65delta3; Nuclear Factor NF Kappa B p65 Subunit; Nuclear factor of kappa light polypeptide gene enhancer in B cells 3; OTTHUMP00000233473; OTTHUMP00000233474; OTTHUMP00000233475; OTTHUMP00000233476; OTTHUMP00000233900; p65 NF kappaB; p65 NFkB; TF65; V rel avian reticuloendotheliosis viral oncogene homolog A; v rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B cells 3 (p65) ) ; V rel reticuloendotheliosis viral oncogene homolog A; v rel reticuloendotheliosis viral oncogene homolog A (avian)

11G4

Unconjugated

WB

Cell Biology; Neuroscience; Microbiology; Signal Transduction; Epigenetics and Nuclear Signaling; Cancer; Cardiovascular; Metabolism

Protein A

1 mg/mL

WB 1:2000-1:20000

10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5

Ice bag

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

https://789.bio/eb/qzJ94JW5

65 kDa

70 kDa

IgG