Recombinant fosfor-p53 (Ser15) monoklonale antilichamen

The p53 tumor suppressor protein is a multi-functional transcription factor that regulates cellular decisions regarding proliferation, cell cycle checkpoints, and apoptosis. The importance of p53 is underscored by its mutation in over 50% of human cancers. Mice that lack one or both copies of p53 also showed an increased incidence of tumors, which makes the p53 deficient mouse a model system for studying cancer generation and progression.

TP53

P04637

Human

A synthetic phosphopeptide corresponding to residues around Ser15 of the Human Phospho-p53

BCC; LFS; TRP; BMFS; Antigen NY-CO; Tumor protein; Phosphoprotein p; Tumor suppressor p; Mutant tumor protein; Cellular tumor antigen p; Transformation related protein; BCC7; LFS1; P53; TRP53; TP53; BMFS5; Antigen NY-CO-13; Cellular tumor antigen p53; FLJ92943; Mutant tumor protein 53; p53 tumor suppressor; Phosphoprotein p53; Transformation related protein 53; Tumor protein 53; Tumor protein p53; Tumor suppressor p53; BCC7; LFS1; P53; TRP53; tumor protein p53; Antigen NY-CO-13; BCC7; Cellular tumor antigen p53; FLJ92943; LFS1; Mutant tumor protein 53; p53; p53 tumor suppressor; P53; Phosphoprotein p53; Tp53; Transformation related protein 53; TRP53; Tumor protein 53; Tumor protein p53; Tumor suppressor p53

11A5

Unconjugated

WB

Cell Biology; Epigenetics and Nuclear Signaling; Cancer

Protein A

1 mg/mL

WB 1:1000-1:5000

10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5

Ice bag

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

https://789.bio/eb/PgvHfX5v

43 kDa

43 kDa

IgG