Recombinant fosfor-PLCγ1 (Tyr783) Monoklonale antilichamen

The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor) -activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.

PLCγ1

P19174

Human; Mouse; Rat

A synthetic peptide corresponding to residues around (Tyr783) of Human Phospho-PLCγ1

PLCG; phospholipase C gamma; NCKAP; PLCgamma; PLC; PLCG1; NCKAP3; PLC-II; PLC1; PLC148; PLCgamma1; phospholipase C gamma 1; NCKAP3; phospholipase C gamma 1; PLC1; PLC148; PLCgamma1; PLC-II; PLCG1

11A1

Unconjugated

WB

Cardiovascular; Signal Transduction; Cancer; Metabolism

Protein A

0.2 mg/mL

WB 1:2000-1:10000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/BpOThVwL

149 kDa

149 kDa

IgG, κ