Recombinant fosfor-PTP1B (Ser386) monoklonale antilichamen

Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.

Phospho-PTP1B (Ser386)

P18031

Human

Recombinant human Phospho-PTP1B (Ser386) fragment

PTPN; PTPN1; PTP1B

A346

Unconjugated

WB; IF

Signal Transduction; Cardiovascular

Protein A purified

1 mg/mL

WB 1:500-1:2000; IF 1:50

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/O025QfSO

50 kDa

50 kDa

IgG, κ