Recombinant fosfor-STAT3 (Ser727) Monoklonaal antilichaam

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein.

Stat3

P40763

Human; Mouse; Rat

A synthetic peptide corresponding to residues around (Ser727) of Human Phospho-STAT3

STAT; Signal Transducer and Activator of Transcription; ADMIO; ADMIO1; APRF; HIES; STAT3; Acute-Phase Response Factor; Signal Transducer and Activator of Transcription 3;1110034C02Rik; Acute Phase Response Factor; AW109958; DNA binding protein APRF; FLJ20882; MGC16063; Signal transducer and activator of transcription 3 (acute phase response factor) ; STAT 3

6H7

Unconjugated

WB; IHC

Signal Transduction; Epigenetics and Nuclear Signaling; Stem Cells; Cancer; Cardiovascular; Developmental Biology

Protein A

0.2 mg/mL

IHC 1:400-1:1000; WB 1:2000-1:10000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/Zx3tjqiG

88 kDa

88 kDa

IgG, κ