Recombinant fosfor-Tau (S262) Monoklonaal antilichaam

Tau is a neuronal microtubule-associated protein, which is mainly located in the cytoplasm, cytoskeleton and cell membrane. Tau is expressed in neuronal tissues and exists in the form of a variety of alternate splicing subtypes. Its C-terminus is combined with axon microtubules, and the N-terminus is combined with neuroplasmic membrane components to maintain the stability and plasticity of the neuronal cytoskeleton. In neurons, hyperphosphorylated and abnormally glycosylated Tau protein accumulates, causing neurofibrosis and neurodegeneration, such as Alzheimer’s disease (AD), frontotemporal dementia, and chronic traumatic encephalopathy (CTE), Parkinson's disease after encephalitis, etc.

Phospho-Tau (S262)

P10636

Human

Recombinant human Tau (phospho S262) fragment

FTDP; PPP1R; DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU; MAPT; Microtubule-Associated Protein Tau; Neurofibrillary Tangle Protein; Paired Helical Filament-Tau; PHF-Tau; pMAPT/pTAU; TAU and MAPT; N/A; AI413597; AW045860; FLJ31424; FTDP 17; G protein beta1/gamma2 subunit interacting factor 1; included; MGC134287; MGC138549; MGC156663; Microtubule associated protein tau; Microtubule associated protein tau isoform 4; Mtapt; Paired helical filament tau; PHF tau; Protein phosphatase 1; pTau; regulatory subunit 103; RNPTAU; Tauopathy and respiratory failure

A408

Unconjugated

WB

Neuroscience; Signal Transduction

Protein A purified

1 mg/mL

WB 1:500-1:2000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/Ws9Ov3Um

79 kDa

50 kDa

IgG, κ