Recombinant fosfor-Tau (Ser199) Monoklonale Antilichaam

Promotes microtubule assembly and stability and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Phospho-Tau (Ser199)

P10636

Human; Rat; Mouse

Phosphorylated human Tau (Ser199) peptide

FTDP; PPP1R; DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU; MAPT; Microtubule-Associated Protein Tau; Neurofibrillary Tangle Protein; Paired Helical Filament-Tau; PHF-Tau; pMAPT/pTAU; TAU and MAPT; N/A; AI413597; AW045860; FLJ31424; FTDP 17; G protein beta1/gamma2 subunit interacting factor 1; included; MGC134287; MGC138549; MGC156663; Microtubule associated protein tau; Microtubule associated protein tau isoform 4; Mtapt; Paired helical filament tau; PHF tau; Protein phosphatase 1; pTau; regulatory subunit 103; RNPTAU; Tauopathy and respiratory failure

A803

Unconjugated

WB; IHC; IF; FCM

Neuroscience; Signal Transduction

Protein A purified

1 mg/mL

WB 1:1000-1:3000; IHC 1:200-1:1000; IF 1:50; FCM 1:50-1:100

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/ckcC5AiA

79 kDa

55 kDa

IgG, κ