Recombinant FOXC1 monoklonaal antilichaam

FoxC1, also named as FKHL7 or FREAC3, is one of two mammalian FoxC subfamily members. Along with FoxC2, it is expressed in paraxial mesoderm where it functions to promote somitogenesis, myogenesis, and vascular development, possibly under Wnt/β-catenin regulation. Mutations in FoxC1 are implicated in anterior segment dysgenesis (ASD) disorders, including congenital glaucoma and Axenfeld-Rieger syndrome. Research studies have shown that alterations in FoxC1 expression are linked to breast cancer invasiveness and have been shown to modulate proliferation and migration of breast cancer cells in vitro.

FOXC1

Q12948

Human

Recombinant human FOXC1 fragment

IHG; FOXC; ASGD; FKHL; IRID; RIEG; FOXC1; ARA; ASGD3; FKHL7; FREAC-3; FREAC3; IGDA; IHG1; IRID1; RIEG3; FKH L7; FKHL 7; Forkhead (Drosophila) like 7; Forkhead box C1; Forkhead box protein C1; Forkhead drosophila homolog like 7; Forkhead like 7; Forkhead related activator 3; Forkhead related protein FKHL7; Forkhead related transcription factor 3; Forkhead-related protein FKHL7; Forkhead-related transcription factor 3; FOX C1; FOXC 1; FREAC 3; IHG 1; IRID 1; Iridogoniodysgenesis type 1; Myeloid factor delta

A663

Unconjugated

WB

Epigenetics and Nuclear Signaling; Developmental Biology

Protein A purified

1 mg/mL

WB 1:1000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/ioGz7ePs

70-74 kDa

70 kDa

IgG, κ