Recombinant Histone H2A (Acetyl Lys5) Monoclonaal antilichaam

Histone post-translational modifications (PTMs), known as the “histone code”, are key mechanisms of epigenetics that modulate chromatin structures. The PTMs on histone including acetylation, methylation, phosphorylation, and novel acylations directly affect the accessibility of chromatin to transcription factors and other epigenetic regulators, altering genome stability and gene transcription. Histone acetylation, tightly controlled by the opposing action of histone acetyltransferases (HATs) and histone deacetylases (HDACs), occurs primarily at lysine residues on the N-terminal tails of histones H2A (Lys5, 9, and 15), H2B (Lys5, 12, 15, 16, and 20), H3 (Lys4, 9, 14, 18, 23, 27, and 36), and H4 (Lys5, 8, 12, 16, and 20), and plays vital roles in the regulation of gene expression, DNA damage repair, chromatin dynamics, etc.

Histone H2A (Acetyl Lys5)

P04908

Human; Rat; Mouse

Acetylated human histone H2A (Lys5) peptide

H2AFM; HIST1H2AB; H2AFA; HIST1H2AE; H2AC4; H2AC8

A109

Unconjugated

WB; ChIP

Epigenetics and Nuclear Signaling

Protein A purified

1 mg/mL

6

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/qRF0JCKQ

14 kDa

14 kDa

IgG, κ