Recombinant Histone H2A.Z Monoklonale Antilichaam

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.

Histone H2A.Z

P0C0S5

Human; Mouse; Rat

Recombinant Human Histone H2A.Z protein

H2AFZ; H2AZ; H2AZ1; Histone H2A.Z

6B1

Unconjugated

IHC

Epigenetics and Nuclear Signaling

Protein A

0.2 mg/mL

IHC 1:200-1:1000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/GshmWMSC

IgG, κ