Recombinant Histone H4 (CT) Monoklonale Antilichaam

Histones are a family of basic proteins that form the core of the nucleosome – the fundamental structural unit of chromatin. In a single nucleosome, core histone proteins H2A, H2B, H3, and H4 form an octamer around which the DNA is tightly wrapped. Histone proteins not only serve to compact chromosomal DNA but also play vital roles in the dynamic and long-term regulation of genes by a wide variety of post-translational modifications (PTMs) . These PTMs including acetylation, methylation, phosphorylation, and novel acylations directly affect the accessibility of chromatin to transcription factors and other epigenetic regulators, altering genome stability and gene transcription. Histone H4 is primarily acetylated at Lys5, 8, 12, and 16, and methylated at Lys20.

Histone H4

P62805

Human; Rat; Mouse; Yeast; Pig

Synthetic peptide corresponding to the C-terminus of human histone H4 protein

H4F; methyl histone H; methylated histone H; HIST2H; HIST1H; HISTH4H; histone H; HIST2H4B; H4/o; histone H4; HIST1H4A; FO108; H4/p; HIST1H4; Hist4h4; HISTH4H4; methyl histone H4; methylated histone H4; H4/A; H4FA; H4/I; H4FI; HIST1H4B; H4/G; H4FG; HIST1H4C; H4/B; H4FB; HIST1H4D; H4/J; H4FJ; HIST1H4E; H4/C; H4FC; HIST1H4F; H4/H; H4FH; HIST1H4H; H4/M; H4FM; HIST1H4I; H4/E; H4FE; H4/D; H4FD; HIST1H4K; H4/K; H4FK; HIST1H4L; H4/N; H4F2; H4FN; HIST2H4; HIST2H4A; H4; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4-16; A; I; H4B; H4J; H4H; H4M; H4E; HIST1H4J; H4D; H4C; H4/p; histone H4; HIST1H4B H4/I

A656

Unconjugated

WB; IHC

Epigenetics and Nuclear Signaling

Protein A purified

1 mg/mL

WB 1:2000-1:10000; IHC 1:50-1:100

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/59JyDBvv

11 kDa

11 kDa

IgG, κ