Recombinant humaan 14-3-3 eta-eiwit

14-3-3 eta also as known as YWHAH. This protein belong to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 eta interacts with and relocalizes the A20 zinc finger protein from the insoluble to the soluble fraction, suggesting a chaperone function. It implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binding to a large number of partners, usually by recognition of a phosphothreonine motif. Recombinant Human 14-3-3 eta was expressed in E. coli and purified by using conventional chromatography techniques.

YWHAH, YWHA1, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta, Protein AS1

E.coli

Human

Non-Tagged

SDS-PAGE

1 mg/mL (determined by absorbance at 280 nm)

> 90% by SDS-PAGE

28.2 kDa (246aa)

1433 eta, YWHAH, YWHA1, ATGP3347-10 µg, ATGP3347-20 µg, ATGP3347-50 µg, ATGP3347-100 µg, ATGP3347-250 µg, ATGP3347-500 µg, ATGP3347-1 mg, ATGP3347-10, ATGP3347-20, ATGP3347-50, ATGP3347-100, ATGP3347-250, ATGP3347-500, ATGP3347-1

Maksymowych WP., et al. (2014) Arthritis Res Ther. 16 (2) : R99.; ; Sato S., et al. (2002) J Biol Chem. 277: 39360-39367

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Signal Transduction

NP_003396

Q04917

Human

MGDREQLLQR ARLAEQAERY DDMASAMKAV TELNEPLSNE DRNLLSVAYK NVVGARRSSW RVISSIEQKT MADGNEKKLE KVKAYREKIE KELETVCNDV LSLLDKFLIK NCNDFQYESK VFYLKMKGDY YRYLAEVASG EKKNSVVEAS EAAYKEAFEI SKEQMQPTHP IRLGLALNFS VFYYEIQNAP EQACLLAKQA FDDAIAELDT LNEDSYKDST LIMQLLRDNL TLWTSDQQDE EAGEGN