Recombinant humaan 2B4/CD244 eiwit

CD244 (Natural Killer Cell Receptor 2B4), also known as Cluster of Differentiation 244, contains 2 Ig-like (immunoglobulin-like) domains. A role for the subtypes of CD2 Ig superfamily receptors has been recently demonstrated in eosinophilic inflammation in experimental asthma and atopic asthmatics. Functions of CD244 molecules are in eosinophil adhesion and chemotaxis, and correlated the results to the pathophysiology of allergic rhinitis (AR) . The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules present on white blood cells initially but found in almost any kind of cell of the body, providing targets for immunophenotyping of cells. Recombinant human CD244 protein, fused to His-tag at N-terminus, was expressed in E. coli.

CD244 molecule natural killer cell receptor 2B4, NAIL, NKR2B4, Nmrk, SLAMF4

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.5 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

25.5 kDa (230aa)

SLAMF4, Nmrk, NKR2B4, Natural killer cell receptor 2B4 isoform 1, natural killer cell receptor 2B4, NAIL, CD244 molecule natural killer cell receptor 2B4, CD244 molecule, CD244, 2B4, ATGP1663-10 µg, ATGP1663-20 µg, ATGP1663-50 µg, ATGP1663-100 µg, ATGP1663-250 µg, ATGP1663-500 µg, ATGP1663-1 mg, ATGP1663-010, ATGP1663-020, ATGP1663-050, ATGP1663-100, ATGP1663-250, ATGP1663-500, ATGP1663-01M

Nakajima H., et al. (1999) Eur. J. Immunol. 29:1676-1683; ; Zola H, et al. (2007) . J Immunol Methods. 318 (1-2) : 1-5.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea

Immunology

NP_057466

Q9BZW8

Human

MGSSHHHHHH SSGLVPRGSH MGSHGKGCQG SADHVVSISG VPLQLQPNSI QTKVDSIAWK KLLPSQNGFH HILKWENGSL PSNTSNDRFS FIVKNLSLLI KAAQQQDSGL YCLEVTSISG KVQTATFQVF VFDKVEKPRL QGQGKILDRG RCQVALSCLV SRDGNVSYAW YRGSKLIQTA GNLTYLDEEV DINGTHTYTC NVSNPVSWES HTLNLTQDCQ NAHQEFRFWP