Recombinant humaan Activine RIIA-eiwit

ACVR2A, also known as activin receptor type-2A, is involved in a wide range of biological processes including mesoderm induction, neural cell differentiation, bone remodeling, hematopoiesis, the regulation of reproductive physiology, inflammation, and carcinogenesis. They function through heteromeric complexes of type I and type II serine/threonine kinase receptors. Recombinant human ACVR2A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Activin receptor type-2A, ACVR2A, ACTRII, ACVR2

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

14.4 kDa (124aa)

Activin RIIA, Activin receptor type-2A, ACVR2A, ACTRII, ACVR2, ATGP3366-10 µg, ATGP3366-20 µg, ATGP3366-50 µg, ATGP3366-100 µg, ATGP3366-250 µg, ATGP3366-500 µg, ATGP3366-1 mg, ATGP3366-10, ATGP3366-20, ATGP3366-50, ATGP3366-100, ATGP3366-250, ATGP3366-500, ATGP3366-1

Welt C., et al. (2002) Exp Biol Med. 227:724-752.; ; Chen YG., et al. (2006) Exp Biol Med. 231:534-544.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Signal Transduction

NP_001607

P27037

Human

Ala20

AILGRSETQE CLFFNANWEK DRTNQTGVEP CYGDKDKRRH CFATWKNISG SIEIVKQGCW LDDINCYDRT DCVEKKDSPE VYFCCCEGNM CNEKFSYFPE MEVTQPTSNP VTPKPPLEHH HHHH