Recombinant humaan ADRM1-eiwit

ADRM1, also known as proteasomal ubiquitin receptor ADRM1, functions as a proteasomal ubiquitin receptor. This protein is an integral plasma membrane protein which promotes cell adhesion. ADRM1 is thought to undergo O-linked glycosylation. Expression of this gene has been shown to be induced by gamma interferon in some cancer cells. Recombinant human ADRM1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Proteasomal ubiquitin receptor ADRM1, ARM1, GP110, Rpn13

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

44.7 kDa (431aa) confirmed by MALDI-TOF

ADRM1, Proteasomal ubiquitin receptor ADRM1, ARM1, GP110, Rpn13, ATGP1498-10 µg, ATGP1498-20 µg, ATGP1498-50 µg, ATGP1498-100 µg, ATGP1498-250 µg, ATGP1498-500 µg, ATGP1498-1 mg, ATGP1498-10, ATGP1498-20, ATGP1498-50, ATGP1498-100, ATGP1498-250, ATGP1498-500, ATGP1498-1

Hamazaki J., et al. (2006) EMBO J. 25:4524-4536; ; Qiu X.-B., et al. (2006) EMBO J. 25:5742-5753

Izaguirre-Carbonell J, et al. Novel anticancer agent, SQAP, binds to focal adhesion kinase and modulates its activity. (Sci Rep. 2015) {https://www.ncbi.nlm.nih.gov/pubmed/26456697}

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT

Cytoskeleton

NP_783163

Q16186

Human

MTTSGA LFPSLVPGSR GASNKYLVEF RAGKMSLKGT TVTPDKRKGL VYIQQTDDSL IHFCWKDRTS GNVEDDLIIF PDDCEFKRVP QCPSGRVYVL KFKAGSKRLF FWMQEPKTDQ DEEHCRKVNE YLNNPPMPGA LGASGSSGHE LSALGGEGGL QSLLGNMSHS QLMQLIGPAG LGGLGGLGAL TGPGLASLLG SSGPPGSSSS SSSRSQSAAV TPSSTTSSTR ATPAPSAPAA ASATSPSPAP SSGNGASTAA SPTQPIQLSD LQSILATMNV PAGPAGGQQV DLASVLTPEI MAPILANADV QERLLPYLPS GESLPQTADE IQNTLTSPQF QQALGMFSAA LASGQLGPLM CQFGLPAEAV EAANKGDVEA FAKAMQNNAK PEQKEGDTKD KKDEEEDMSL D