Recombinant humaan AICL/CLEC2B-eiwit

CLEC2B, also known as C-type lectin domain family 2 member B, is a type-2 transmembrane member of the C-type lectin-like receptor (CTLR) family. They play diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. This protein may function as a cell activation antigen. It has variant roles such as activating receptor that triggers TNF production, NK cell mediated lysis and interactions between activated and resting NK cells. Recombinant human CLEC2B protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

C-type lectin domain family 2 member B, Activation-induced C-type lectin, C-type lectin superfamily member 2, IFN-alpha-2b-inducing-related protein 1, AICL, CLECSF2, IFNRG1, HP10085IFNRG1

Baculovirus

Human

HIgG-His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

41.7 kDa (366aa)

AICL, CLEC2B, C-type lectin domain family 2 member B, CLEC2B, AICL, CLECSF2, HP10085, IFNRG1, ATGP3797-10 µg, ATGP3797-20 µg, ATGP3797-50 µg, ATGP3797-100 µg, ATGP3797-250 µg, ATGP3797-500 µg, ATGP3797-1 mg, ATGP3797-10, ATGP3797-20, ATGP3797-50, ATGP3797-100, ATGP3797-250, ATGP3797-500, ATGP3797-1

Pollitt AY., et al, (2010) Blood. 115:2938-2946.; ; Hughes CE., et al, (2013) J Biol Chem. 288:5127-5135.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_005118

Q92478

Human

Ala

ADPKLTRDSQ SLCPYDWIGF QNKCYYFSKE EGDWNSSKYN CSTQHADLTI IDNIEEMNFL RRYKCSSDHW IGLKMAKNRT GQWVDGATFT KSFGMRGSEG CAYLSDDGAA TARCYTERKW ICRKRIHLEP KSCDKTHTCP PCPAPELLGG PSVFLFPPKP KDTLMISRTP EVTCVVVDVS HEDPEVKFNW YVDGVEVHNA KTKPREEQYN STYRVVSVLT VLHQDWLNGK EYKCKVSNKA LPAPIEKTIS KAKGQPREPQ VYTLPPSRDE LTKNQVSLTC LVKGFYPSDI AVEWESNGQP ENNYKTTPPV LDSDGSFFLY SKLTVDKSRW QQGNVFSCSV MHEALHNHYT QKSLSLSPGK HHHHHH