Recombinant humaan AIF-1/Iba1-eiwit

AIF1 (Allograft inflammatory factor 1) is induced by cytokines and interferon. This protein is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. AIF1 is a cytoplasm, calcium-binding protein whose expression in transplanted human hearts correlates with rejection and development of coronary artery vasculopathy (CAV) . Recombinant human AIF1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Allograft inflammatory factor 1, AIF-1, IBA1, IRT-1, IRT1

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

18.9 kDa (167aa) confirmed by MALDI-TOF

AIF1, Iba1, Allograft inflammatory factor 1, AIF-1, IBA1, IRT-1, IRT1, ATGP1006-10 µg, ATGP1006-20 µg, ATGP1006-50 µg, ATGP1006-100 µg, ATGP1006-250 µg, ATGP1006-500 µg, ATGP1006-1 mg, ATGP1006-10, ATGP1006-20, ATGP1006-50, ATGP1006-100, ATGP1006-250, ATGP1006-500, ATGP1006-1

Kelemen S.E., et al (2005) Am. J. Pathol. 167:619-626; ; Schulze J.O., et al. (2008) FEBS J. 275:4627-4640

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 200 mM NaCl

Immunology

NP_001614

P55008

Human

MGSSHHHHHH SSGLVPRGSH MSQTRDLQGG KAFGLLKAQQ EERLDEINKQ FLDDPKYSSD EDLPSKLEGF KEKYMEFDLN GNGDIDIMSL KRMLEKLGVP KTHLELKKLI GEVSSGSGET FSYPDFLRMM LGKRSAILKM ILMYEEKARE KEKPTGPPAK KAISELP