Recombinant humaan AIP-eiwit

Aryl hydrocarbon receptor (AHR) interacting protein, also known as AIP, may play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting. It is a Cellular negative regulator of the hepatitis B virus (HBV) X protein. Also, AIP is a ubiquitously expressed protein, binds to HSP 90 and AHR through a highly conserved carboxy-terminal tetraticopeptide repeat domain. Recombinant human AIP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

AH receptor-interacting protein, Aryl-hydrocarbon receptor-interacting protein, HBV X-associated protein 2, XAP-2, Immunophilin homolog ARA9, Aryl hydrocarbon receptor-associated protein 9, FKBP16, FKBP prolyl isomerase 16, FK506-binding protein 37, FKBP37

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

39.8 kDa (350aa) confirmed by MALDI-TOF

AIP, Aryl hydrocarbon receptor interacting protein, ARA9, FKBP37, XAP2, ATGP1137-10 µg, ATGP1137-20 µg, ATGP1137-50 µg, ATGP1137-100 µg, ATGP1137-250 µg, ATGP1137-500 µg, ATGP1137-1 mg, ATGP1137-10, ATGP1137-20, ATGP1137-50, ATGP1137-100, ATGP1137-250, ATGP1137-500, ATGP1137-1

Kazlauskas A., et al. (2000) J Biol Chem. 275:41317-41324.; ; Meyer BK., et al. (1998) Mol Cell Biol. 18:978-988.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol

Signal Transduction

AAI04828

O00170

Human

MADIIARLRE DGIQKRVIQE GRGELPDFQD GTKATFHYRT LHSDDEGTVL DDSRARGKPM ELIIGKKFKL PVWETIVCTM REGEIAQFLC DIKHVVLYPL VAKSLRNIAV GKDPLEGQRH CCGVAQMREH SSLGHADLDA LQQNPQPLIF HMEMLKVESP GTYQQDPWAM TDEEKAKAVP LIHQEGNRLY REGHVKEAAA KYYDAIACLK NLQMKEQPGS PEWIQLDKQI TPLLLNYCQC KLVVEEYYEV LDHCSSILNK YDDNVKAYFK RGKAHAAVWN AQEAQADFAK VLELDPALAP VVSRELRALE ARIRQKDEED KARFRGIFSH