Recombinant humaan ALDOC-eiwit

ALDOC, also as known as fructose bisphosphate C, is a member of the class 1 fructose-biphosphate aldolase family. This protein is a ubiquitous enzyme that catalyzes the reversible aldol cleavage of fructose-bisphosphate and fructose 1-phospate to digydroxyacetone phosphate and either glyceral-dehyde-3-phosphate or glyceraldegyde, respectively. It is expressed specifically in the hippocampus and Purkinje cells of the brain. Recombinant human ALDOC was expressed in E. coli and purified by using conventional chromatography techniques.

Fructose bisphosphate aldolase C, ALDC, ALDC, ALDO C, aldoc, ALDOC_HUMAN, Aldolase 3, Aldolase C Fructose bisphosphate, Brain type aldolase, Brain-type aldolase, Fructoaldolase C, Fructose 1 6 biphosphate triosephosphate lyase, Fructose bisphosphate aldolase C, Fructose-bisphosphate aldolase C

E.coli

Human

Non-Tagged

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

39.4 kDa (364aa) confirmed by MALDI-TOF

ALDOC, Fructose bisphosphate aldolase C , ALDC, ALDC, ALDO C, aldoc, ALDOC_HUMAN, Aldolase 3, Aldolase C Fructose bisphosphateBrain type aldolase, Brain-type aldolaseFructoaldolase C, Fructose 1 6 biphosphate triosephosphate lyase, Fructose bisphosphate aldolase C, Fructose-bisphosphate aldolase C, ATGP3393-10 µg, ATGP3393-20 µg, ATGP3393-50 µg, ATGP3393-100 µg, ATGP3393-250 µg, ATGP3393-500 µg, ATGP3393-1 mg, ATGP3393-10, ATGP3393-20, ATGP3393-50, ATGP3393-100, ATGP3393-250, ATGP3393-500, ATGP3393-1

Rolland T. et al., (2014) Cell. 159 (5) :1212-26.; ; Caspi M. et al., (2014) Mol Cancer. 13:164.; ; Arakaki TL. et al., (2004) Protein Sci. 13 (12) : 3077-84

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 2mM DTT, 0.1M NaCl

Cancer

NP_005156.1

P09972

Human

MPHSYPALSA EQKKELSDIA LRIVAPGKGI LAADESVGSM AKRLSQIGVE NTEENRRLYR QVLFSADDRV KKCIGGVIFF HETLYQKDDN GVPFVRTIQD KGIVVGIKVD KGVVPLAGTD GETTTQGLDG LSERCAQYKK DGADFAKWRC VLKISERTPS ALAILENANV LARYASICQQ NGIVPIVEPE ILPDGDHDLK RCQYVTEKVL AAVYKALSDH HVYLEGTLLK PNMVTPGHAC PIKYTPEEIA MATVTALRRT VPPAVPGVTF LSGGQSEEEA SFNLNAINRC PLPRPWALTF SYGRALQASA LNAWRGQRDN AGAATEEFIK RAEVNGLAAQ GKYEGSGEDG GAAAQSLYIA NHAY