Recombinant humaan ALK-1-eiwit

ACVRL1, also known as serine/threonine-protein kinase receptor R3, is a membrane-anchored proteoglycan whose core protein binds TGFf3 and has a short cytoplasmic domain with no discernible signaling structure. Also, this protein shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Recombinant human ACVRL1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

ACVRL1, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I

Baculovirus

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

11.5 kDa (103aa)

ALK1, ACVRL1, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I, ATGP3205-10 µg, ATGP3205-20 µg, ATGP3205-50 µg, ATGP3205-100 µg, ATGP3205-250 µg, ATGP3205-500 µg, ATGP3205-1 mg, ATGP3205-10, ATGP3205-20, ATGP3205-50, ATGP3205-100, ATGP3205-250, ATGP3205-500, ATGP3205-1

Chien CY., et al. (2013) Otolaryngol Head Neck Surg. 148 (6) :965-973.; ; Yu Q., et al. (2013) PLoS ONE. 8 (2) :E58031.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cardiovascular

NP_000011.2

P37023

Human