Recombinant humaan ALK-6/BMPR1B eiwit

BMPR1B also known as bone morphogenetic protein receptor type-1B isoform b. BMPR1B is on ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. It's receptor for BMP7/OP-1 and GDF5. Recombinant human BMPR1B was expressed in E. coli and purified by using conventional chromatography techniques

Bone morphogenetic protein receptor type-1B isoform b, ALK-6, ALK6, CDw293, BMP type-1B receptor, BMPR-1B

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 80% by SDS-PAGE

15.1 kDa (136aa) confirmed by MALDI-TOF

BMPR-IB, ALK6, Bone morphogenetic protein receptor type-1B isoform b, ALK-6, ALK6, CDw293, ATGP3104-10 µg, ATGP3104-20 µg, ATGP3104-50 µg, ATGP3104-100 µg, ATGP3104-250 µg, ATGP3104-500 µg, ATGP3104-1 mg, ATGP3104-10, ATGP3104-20, ATGP3104-50, ATGP3104-100, ATGP3104-250, ATGP3104-500, ATGP3104-1

Ide H., et al. (1997) Oncogene 14:1377-1382.; ; Greenman C., et al. (2007) Nature 446:153-158.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol, 1mM DTT, 0.1mM PMSF

Epigenomics (Transcription & Translation)

NP_001243723

O00238

Human

MGSSHHHHHH SSGLVPRGSH MGSKKEDGES TAPTPRPKVL RCKCHHHCPE DSVNNICSTD GYCFTMIEED DSGLPVVTSG CLGLEGSDFQ CRDTPIPHQR RSIECCTERN ECNKDLHPTL PPLKNRDFVD GPIHHR