Recombinant humaan APOBEC4-eiwit

The APOBEC4 is a member of the AID/APOBEC family of polynucleotide (deoxy) cytidine deaminases, which convert cytidine to uridine. Other AID/APOBEC family members are involved in Mrna editing, somatic hypermutation and recombination of immunoglobulin genes, and innate immunity to retroviral infection. Recombinant human APOBEC4 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Putative C->u-editing enzyme APOBEC-4, C1orf169

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

44 kDa (390aa)

APOBEC4, putative C->u-editing enzyme APOBEC-4, C1orf169, ATGP2392-10 µg, ATGP2392-20 µg, ATGP2392-50 µg, ATGP2392-100 µg, ATGP2392-250 µg, ATGP2392-500 µg, ATGP2392-1 mg, ATGP2392-10, ATGP2392-20, ATGP2392-50, ATGP2392-100, ATGP2392-250, ATGP2392-500, ATGP2392-1

Prochnow, C., et al. (2009) Sci. China, C, Life Sci. 52 (10), 893-902; ; Rogozin, I.B., et al. (2005) Cell Cycle 4 (9), 1281-1285;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Epigenomics (Transcription & Translation)

NP_982279

Q8WW27

Human

MEPIYEE YLANHGTIVK PYYWLSFSLD CSNCPYHIRT GEEARVSLTE FCQIFGFPYG TTFPQTKHLT FYELKTSSGS LVQKGHASSC TGNYIHPESM LFEMNGYLDS AIYNNDSIRH IILYSNNSPC NEANHCCISK MYNFLITYPG ITLSIYFSQL YHTEMDFPAS AWNREALRSL ASLWPRVVLS PISGGIWHSV LHSFISGVSG SHVFQPILTG RALADRHNAY EINAITGVKP YFTDVLLQTK RNPNTKAQEA LESYPLNNAF PGQFFQMPSG QLQPNLPPDL RAPVVFVLVP LRDLPPMHMG QNPNKPRNIV RHLNMPQMSF QETKDLGRLP TGRSVEIVEI TEQFASSKEA DEKKKKKGKK