Recombinant humaan Apolipoproteïne E/ApoE (C-His, Expi293)

Source : Human 293 Cells; Apolipoprotein E (ApoE) is a glycoprotein that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. ApoE can be synthesized by the liver and intestinally synthesized chylomicrons. ApoE mediates high-affinity binding of chylomicrons and very low density lipoprotein (VLDL) particles to the LDL receptor, allowing for specific uptake of these particles by the liver, preventing the accumulation of cholesterol-rich particles in the plasma. ApoE plays an essential role in the formation of plasma lipoproteins and is involved in their production, conversion and clearance. ApoE is also a constituent of a subclass of high density of lipoproteins (HDL) involved in cholesterol transport.

AD2; LPG; APO-E; LDLCQ5; apolipoprotein E; apolipoprotein E3

Lyophilized from a 0.2 um filtered solution of 2umM PBS, 5mM CHAPS, 2mM DDT, pH7.4

Ambient

Recombinant Human Apolipoprotein E is produced by Human 293 Cells and the target gene encoding Lys19-His317 is expressed with a 6His tag at the C-terminus.