Recombinant humaan ARC-eiwit

Activity-regulated cytoskeleton-associated protein, also known as ARC, is required for consolidation of synaptic plasticity as well as formation of long-term memory. This protein regulates endocytosis of AMPA receptors in response to synaptic activity. This protein required for homeostatic synaptic scaling of AMPA receptors. This protein plays a role in the regulation of cell morphology and cytoskeletal organization. Recombinant human ARC protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Activity-regulated cytoskeleton-associated protein, Arg3.1, KIAA0278

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

47.4 kDa (416aa) confirmed by MALDI-TOF

ARC, Activity-regulated cytoskeleton-associated protein, Arg3.1, KIAA0278, ATGP2016-10 µg, ATGP2016-20 µg, ATGP2016-50 µg, ATGP2016-100 µg, ATGP2016-250 µg, ATGP2016-500 µg, ATGP2016-1 mg, ATGP2016-10, ATGP2016-20, ATGP2016-50, ATGP2016-100, ATGP2016-250, ATGP2016-500, ATGP2016-1

Nagase T., et al. (1996) DNA Res. 3:321-329

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT

Neuroscience

NP_056008

Q7LC44

Human

MGSSHHHHHH SSGLVPRGSH MELDHRTSGG LHAYPGPRGG QVAKPNVILQ IGKCRAEMLE HVRRTHRHLL AEVSKQVERE LKGLHRSVGK LESNLDGYVP TSDSQRWKKS IKACLCRCQE TIANLERWVK REMHVWREVF YRLERWADRL ESTGGKYPVG SESARHTVSV GVGGPESYCH EADGYDYTVS PYAITPPPAA GELPGQEPAE AQQYQPWVPG EDGQPSPGVD TQIFEDPREF LSHLEEYLRQ VGGSEEYWLS QIQNHMNGPA KKWWEFKQGS VKNWVEFKKE FLQYSEGTLS REAIQRELDL PQKQGEPLDQ FLWRKRDLYQ TLYVDADEEE IIQYVVGTLQ PKLKRFLRHP LPKTLEQLIQ RGMEVQDDLE QAAEPAGPHL PVEDEAETLT PAPNSESVAS DRTQPE