Recombinant humaan ASPA-eiwit

ASPA also known as aspartoacylase, is expressed in liver, lung and kidney tissue, as well as in skeletal muscle and in cerebral white matter. Existing as a homodimer, ASPA functions to catalyze the deacetylation of N-acetylaspartic acid (NAA) (a protein whose hydrolysis is crucial to maintenance of intact white matter) to produce acetate and L-aspartate. Recombinant human ASPA, was expressed in E. coli and purified by conventional chromatography techniques.

ACY2, ASP

E.coli

Human

Non-Tagged

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

35.7 kDa (313aa)

ASPA, ACY2, ASP, ATGP3289-10 µg, ATGP3289-20 µg, ATGP3289-50 µg, ATGP3289-100 µg, ATGP3289-250 µg, ATGP3289-500 µg, ATGP3289-1 mg, ATGP3289-10, ATGP3289-20, ATGP3289-50, ATGP3289-100, ATGP3289-250, ATGP3289-500, ATGP3289-1

Le Coq., et al. (2006) Biochemistry 45: 5878-5884.; ; Le Coq., et al. (2008) Biochemistry 47: 3484-3492.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Neuroscience

NP_000040

P45381

Human

MTSCHIAEEH IQKVAIFGGT HGNELTGVFL VKHWLENGAE IQRTGLEVKP FITNPRAVKK CTRYIDCDLN RIFDLENLGK KMSEDLPYEV RRAQEINHLF GPKDSEDSYD IIFDLHNTTS NMGCTLILED SRNNFLIQMF HYIKTSLAPL PCYVYLIEHP SLKYATTRSI AKYPVGIEVG PQPQGVLRAD ILDQMRKMIK HALDFIHHFN EGKEFPPCAI EVYKIIEKVD YPRDENGEIA AIIHPNLQDQ DWKPLHPGDP MFLTLDGKTI PLGGDCTVYP VFVNEAAYYE KKEAFAKTTK LTLNAKSIRC CLH