Recombinant humaan B7-H4-eiwit

The VCTN1 is a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. Recombinant human VTCN1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

V-set domain containing T cell activation inhibitor 1, B7-H4, B7h.5, B7H4, B7S1, B7X, PRO1291, RP11-229A19.4, VCTN1

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

28.2 kDa (258aa)

B7-H4, V-set domain containing T cell activation inhibitor 1, B7-H4, B7h.5, B7H4, B7S1, B7X, PRO1291, RP11-229A19.4, VCTN1, ATGP2478-10 µg, ATGP2478-20 µg, ATGP2478-50 µg, ATGP2478-100 µg, ATGP2478-250 µg, ATGP2478-500 µg, ATGP2478-1 mg, ATGP2478-10, ATGP2478-20, ATGP2478-50, ATGP2478-100, ATGP2478-250, ATGP2478-500, ATGP2478-1

Fauci, J.M., et al. (2012) Gynecol. Oncol. 127 (2), 420-425; ; Galazka, K., et al. (2012) Am. J. Reprod. Immunol. 68 (1), 85-93;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol

Cancer

NP_078902

Q7Z7D3

Human

MGSSHHHHHH SSGLVPRGSH MGSLIIGFGI SGRHSITVTT VASAGNIGED GILSCTFEPD IKLSDIVIQW LKEGVLGLVH EFKEGKDELS EQDEMFRGRT AVFADQVIVG NASLRLKNVQ LTDAGTYKCY IITSKGKGNA NLEYKTGAFS MPEVNVDYNA SSETLRCEAP RWFPQPTVVW ASQVDQGANF SEVSNTSFEL NSENVTMKVV SVLYNVTINN TYSCMIENDI AKATGDIKVT ESEIKRRSHL QLLNSKAS