Recombinant humaan BAALC-eiwit

Brain and acute leukemia, cytoplasmic (BAALC) is localizes to both the membrane and the cytoplasm and exists as multiple alternatively spliced isoforms. Expressed by hematopoetic and neural cells, BAALC interacts with CaMKIIalpha and is thought to play a role in synaptic function at postsynaptic lipid rafts. Overexpression of BAALC concomitant predict adverse clinical outcome and may define important risk factor in cytogenetically normal acute myeloid leukemia (AML) . Recombinant human BAALC, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Brain and acute leukemia cytoplasmic isoform 1, Brain and acute leukemia, cytoplasmic isoform 1 Brain and acute leukemia cytoplasmic, FLJ12015.

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

17.7 kDa (165aa) confirmed by MALDI-TOF

BAA, Brain and acute leukemia cytoplasmic isoform 1, Brain and acute leukemia, cytoplasmic isoform 1 Brain and acute leukemia cytoplasmic, FLJ12015., ATGP0438-10 µg, ATGP0438-20 µg, ATGP0438-50 µg, ATGP0438-100 µg, ATGP0438-250 µg, ATGP0438-500 µg, ATGP0438-1 mg, ATGP0438-10, ATGP0438-20, ATGP0438-50, ATGP0438-100, ATGP0438-250, ATGP0438-500, ATGP0438-1

Tanner SM., et al. (2001) Proc Natl Acad Sci u S A. 98 (24) :13901-6. ; ; Satoskar AA., et al. (2005) Gene Expr Patterns. 5 (4) :463-73. ;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 2mM EDTA

Neuroscience

NP_079088

Q8WXS3

Human

MGCGGSRADA IEPRYYESWT RETESTWLTY TDSDAPPSAA APDSGPEAGG LHSGMLEDGL PSNGVPRSTA PGGIPNPEKK TNCETQCPNP QSLSSGPLTQ KQNGLQTTEA KRDAKRMPAK EVTINVTDSI QQMDRSRRIT KNCVN